Yes. Some venues have the ability to set their fire alarm to performance mode. This isolates the smoke detectors in the performance area, but leaves the rest of the building protected. If the fire alarm does not have a performance mode, isolating the smoke detectors in the building can usually be done for the duration of the performance so long as the break glass call points are still active and that the venue staff are aware that the smoke detectors have been isolated. THE FIRE ALARM MUST NEVER BE SWITCHED OFF. You should always check with the venue to determine their procedures for isolating the fire alarm